Figure 1

Morphological analysis of the seminiferous epithelium of male adult mice treated with BPP-10c and captopril. Photomicrographs of the seminiferous tubules of male adult mice treated with vehicle (A), captopril (B) and BPP-10c (C, D, E, F) using Mallory’s trichrome stain. The seminiferous tubule morphological data obtained from the animals treated with BPP-10c indicated the presence of atypical cells in the lumen (arrow), disruption of the epithelium (*), and a loss of elongated spermatids (#). No alteration was observed in the seminiferous epithelium from mice treated with captopril or vehicle.