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Table 1 Quantitative analysis of germinal cells in male adult mouse seminiferous epithelium treated with vehicle (C), captopril (CAP) or BPP-10c (10c)

From: A bradykinin-potentiating peptide (BPP-10c) from Bothrops jararaca induces changes in seminiferous tubules

Germinal cells

Stages

I

V

VII/VIII

XII

C

10c

CAP

C

10c

CAP

C

10c

CAP

C

10c

CAP

SC

4.0 ± 0.8

4.7 ± 0.5

5.0 ± 0.8

4.5 ± 0.5

4.2 ± 0.9

5.0 ± 0.9

5.2 ± 0.5

4.7 ± 0.9

5.1 ± 0.4

5.2 ± 0.5

5.5 ± 0.5

5.8 ± 0.9

SPG(A)

3.5 ± 0.5

4.0 ± 0.5

4.6 ± 0.9

         

SPG(B)

   

5.2 ± 0.5

4.5 ± 0.5

5.5 ± 0.5

      

SP(Pl)

      

13.2 ± 0.5

13.0 ± 0.8

12.7 ± 1.2

   

SP(Z)

         

12.2 ± 0.5

11.0 ± 0.8

12.4 ± 1.5

MF

         

9.7 ± 0.5

9.0 ± 0.5

8.9 ± 0.8

SS

         

6.2 ± 0.5

5.2 ± 0.9

5.1 ± 0.9

SP(P)

10.5 ± 0.5

10.0 ± 0.8

10.9 ± 1.0

12.0 ± 0.8

12.2 ± 0.8

13.0 ± 1.2

19.2 ± 0.5

19.0 ± 0.8

20.1 ± 1.5

   

RP

14.0 ± 0.8

27.0 ± 0.9*

15.0 ± 1.8

14.7 ± 0.5

19.0 ± 0.8*

15.7 ± 0.9

15.0 ± 0.8

30.0 ± 0.8*

16.2 ± 0.8

   
  1. C: control; 10c: BPP-10c; CAP: captopril; SC: Sertoli cell; SPG(A): type A spermatogonia; SPG(B): type B spermatogonia; SP (Pl, Z, P): spermatocyte (preleptotene zygotene, pachytene); MF: meiotic figures; SS: secondary spermatocyte; RP: round spermatid.
  2. Values are the means ± SEM. Significant difference from the C and CAP values p < 0.01 (*).