Use of antivenoms for the treatment of envenomation by Elapidae snakes in Guinea, Sub-Saharan Africa

Table 7 Antivenom doses and mortality observed in the literature

Countries	Patients (n)	Mean doses (mL [range])	# deaths (CFR)	Supportive measures*	Reference
Guinea	26	25 ml	4 (15%)	No	Group 2 this study
		[10–60]
Guinea	17	40 mL	3 (18%)	No	Group 3 this study
		[40–60]
India	28	150 mL	0	VS	[16]
India	27	600 mL	3 (11%)	VS	[16]
		[300–1.600]
Sri Lanka	87	> 100 mL	5 (6%)	VS	[17]
		[100–200]
Sri Lanka	25	100 mL	2 (8%)^§	VS	[18]
		[80–200]
India	37	150 mL	11 (22%)^*	VS; AC	[19]
Taiwan	22	30 mL	0	VS	[20]
		[10–100]
Papua New Guinea	139	50 mL	6 (4.3%)	VS	[13]
Papua New Guinea	31	25 mL	0	VS; AC	[13]
India	14	60 mL	1 (7%)	VS	[21]
India	12	120 mL	0	VS	[21]
Thailand	68	100 mL	0	VS	[22]
India	86	510 mL	3 (3.5%)	VS	[23]
		[50–1900]
Papua New Guinea	156	50 mL	3 (1.9%)	VS	[14]
Vietnam	42	50 mL	0	VS	[24]
		[50–100]
Thailand	85	40 mL	1 (1%)	VS	[25]
		[10–200]

VS: ventilatory support; AC: anticholinesterase; ^§the patients died from extensive necrosis; ^*three patients died before treatment.

ISSN: 1678-9199