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Table 1 Experimental treatments in septic arthritis

From: Septic arthritis: immunopathogenesis, experimental models and therapy

Treatment

Control of arthritis development (*)

Reference

Inhibition of transcription factors NF-kB and mCoAP-1 alone or with antibiotics

No

[71]

Cloxacillin + phenyl-N-tert-butyl nitrone (antioxidant)

Yes

[72]

Cloxacillin + TNF inhibitor

Yes

[60]

Ampicillin + riboflavin (antioxidant)

Yes

[73]

Gentamicin + ascorbic acid

Yes

[74]

Estradiol

Yes

[75]

Azithromycin + riboflavin

Yes

[76]

Glutaminyl cyclase inhibitors

Yes

[77]

  1. (*) Control of arthritis development was assessed by the following parameters: delayed disease development, less severe clinical manifestations or reduced swelling or synovitis.