Neuromuscular activity of methanolic extract of R. schneideri in vertebrate nerve–muscle preparations. (A) Neuromuscular response produced by methanolic extract in indirectly stimulated mouse PND preparations. (B) Individual myographic record. Note the facilitatory response without neuromuscular blockade. (W, wash; Bar: 5 g). The points represent the mean ± S.E.M. of 5–6 experiments. *p < 0.05 compared to the twitch-tension at time 0.