Figure 2From: Presynaptic neuromuscular action of a methanolic extract from the venom of Rhinella schneideri toadElectrofisiological measurements in PND preparations. (A) Changes in the frequency of miniature end-plate potentials (MEPPs) in phrenic nerve-diaphragm preparations incubated with a methanolic extract of R. schneideri venom (50 μg/mL). Insets I and II in A: recordings at time zero (0) and after incubation with extract for 60 minutes, respectively. (B) Changes in the quantal content (end-plate potentials) of phrenic nerve-diaphragm preparations incubated with a methanolic extract of R. schneideri venom (50 μg/mL) for up to 60 minutes and the effect of pretreatment with ouabain (1 μg/mL). The columns are the mean ± S.E.M. (n = 5), *p < 0.05 compared to control preparations.Back to article page