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Table 3 Changes in antioxidant state of rats induced by Naja haje snake venom after four hours

From: Hepatotoxicity and oxidative stress induced by Naja haje crude venom

Parameters

Control rats

Intoxicated rats

Serum GSH (mmol/mL)

1.56 ± 0.34

1.01 ± 0.15*

Liver GSH (mmol/g tissue)

92.42 ± 17.07

56.69 ± 2.46*

Liver GPx (U/g tissue)

1722.43 ± 69.54

2253.41 ± 71.24*

Liver GR (μmol/h/g tissue)

93.78 ± 10.75

55.59 ± 18.27*

Liver GST (μmol/h/g tissue)

0.61 ± 0.02

0.24 ± 0.01*

Liver SOD (U/g tissue)

1.06 ± 0.03

1.72 ± 0.08*

Liver CAT (U/g tissue)

0.41 ± 0.02

0.13 ± 0.01*

  1. *significant change at p < 0.05 with respect to the control group; values are means ± SE (n = 6).
  2. GSH: glutathione, GPx: glutathione peroxidase, GR: glutathione reductase, SOD: superoxide dismutase, CAT: catalase.