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Table 2 Minimum inhibitory concentration (MIC) of the microcystin variant [D-Leu 1 ] MC-LR from extracts of M. aeruginosa RST 9501 and MC-LR (commercially available) against M. tuberculosis strains

From: Antimycobacterial and cytotoxicity activity of microcystins

Microcystin variant

M. tuberculosis

  

H 37 Rv (μM)

 

RMPr (μM)

 

INHr (μM)

[D-Leu1] MC-LR

S

13.2

S

13.2

S

26.5

MC-LR

R

>53

R

>53

R

>53

  1. [D-Leu1] MC-LR: microcystin isolated from the extract of Microcystis RST 9501; MC-LR: commercially obtained; R: resistant; S: sensitive; H37Rv: sensitive strain; INHr: isoniazid-resistant strain; RMPr: rifampicin-resistant strain. Extracts with MIC > 53 μM were considered inactive.