Fig. 2

Formalin test for assessment of the nociceptive activity in rats of a P. regalis, b C. darlingi, and c B. epicureanum venoms at three different doses (5, 10, and 20 μg protein/paw). Nociceptive behavior in phase 1 (0–10 min post-injection) and phase 2 (10–50 min post-injection) was scored as the amount of time spent licking the injected paw. *Significant difference when compared with the negative control injected with saline solution (p < 0.05)