|
Compounds
|
Examples
|
Species
|
Molecular Mass (kDa)a
|
Mechanism of Action
|
References
|
|---|
|
Enzyme Inhibitors
|
Amblyomin-Xb
|
Amblyomma cajennense
|
15.0
|
Factor Xa Inhibition/induction of apoptosis in tumor cells
|
134–136
|
|
Savignin
|
Ornithodoros savignyi
|
14.1
|
Thrombin inhibitor
|
137–138
|
|
Ixolaris
|
Ixodes scapularis
|
18.4
|
Tissue factor pathway inhibitor
|
139–140
|
|
Variegin
|
Amblyomma variegatum
|
3.6
|
Thrombin inhibitor
|
145
|
|
Neurotoxin
|
HT-1 (Holocyclotoxins)
|
Ixodes holocyclus
|
7.8
|
Unclear
|
114, 146–148
|
|
Enzyme
|
Phospholipase A2
|
Amblyomma americanum
|
55.7 ± 1.3
|
Hydrolysis of membrane phospholipids
|
158–159
|
|
Proteins
|
Hebraein
|
Amblyomma hebraeum
|
11.0
|
Unclear
|
163
|
|
Ixosin
|
Ixodes sinensis
|
8.8
|
Unclear
|
165
|
|
ISAMP
|
Ixodes scapularis
|
5.3
|
Unclear
|
167
|
-
aData obtained from references and uniprot.org
-
bCompound found only in the transcriptome
