Fig. 5

Means ± standard deviation of the mean (p < 0.05) of NO production in supernatant of murine macrophages infected by L. (L.) chagasi treated with PLA₂ at three different incubation moments: (a) 24 h, (b) 48 h, and (c) 72 h. The control was done without treatment (MO) and with lipopolysaccharide (LPS). The PLA₂ doses utilized in the treatment (T) were T1 = 100 μg/mL; T2 = 50 μg/mL; T3 = 25 μg/mL; T4 = 12.5 μg/mL; Tr5 = 6.25 μg/mL; T6 = 3.125 μg/mL; T7 = 1.5625 μg/mL; T8 = 0.78125 μg/mL