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Table 2 Genotype and allele frequencies of −308 G > A polymorphism of the TNF-α gene, adjusted for the presence of. H pylori in patients with normal gastric mucosa, gastritis and gastric cancer

From: Lack of association among TNF-α gene expression, -308 polymorphism (G > A) and virulence markers of Helicobacter pylori

  Normal (n = 40) Chronic gastritis (n = 70) Gastric cancer (n = 24)
  Hp + (n: 03) Hp - (n: 37) Hp + (n: 47) Hp - (n: 23) OR (95 % CI), p Hp + (n: 21) Hp - (n: 03) OR (95 % CI, p
Genotypes
 G/G 03 (100 %) 30 (81 %) 34 (72.3 %) 18 (78.3 %) 1.55 (0.48-4.98), 0.46 15 (71.4 %) 02 (66.6 %) 3.66 (0.48-27.85), 0.2
 G > A 04 (10.9 %) 09 (19.1 %) 05 (21.7 %) 03 (14.3 %) 01 (33.4 %)
 A/A 03 (8.1 %) 04 (8.6 %) 03 (14.3 %)
Alleles         
 G 6 (100 %) 64 (86.5 %) 77 (82 %) 41 (89 %) 1.36 (0.61- 3.03), 0.55 33 (78.5 %) 05 (83.3 %) 1.84 (0.70- 4.81),021
 A 10 (13.5 %) 17 (18 %) 05 (11 %)   09 (21.5 %) 01 (16.7 %)  
  1. Hp: Helicobacter pylori; n: number of samples