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Table 2 Genotype and allele frequencies of −308 G > A polymorphism of the TNF-α gene, adjusted for the presence of. H pylori in patients with normal gastric mucosa, gastritis and gastric cancer

From: Lack of association among TNF-α gene expression, -308 polymorphism (G > A) and virulence markers of Helicobacter pylori

 

Normal (n = 40)

Chronic gastritis (n = 70)

Gastric cancer (n = 24)

 

Hp + (n: 03)

Hp - (n: 37)

Hp + (n: 47)

Hp - (n: 23)

OR (95 % CI), p

Hp + (n: 21)

Hp - (n: 03)

OR (95 % CI, p

Genotypes

 G/G

03 (100 %)

30 (81 %)

34 (72.3 %)

18 (78.3 %)

1.55 (0.48-4.98), 0.46

15 (71.4 %)

02 (66.6 %)

3.66 (0.48-27.85), 0.2

 G > A

04 (10.9 %)

09 (19.1 %)

05 (21.7 %)

03 (14.3 %)

01 (33.4 %)

 A/A

03 (8.1 %)

04 (8.6 %)

03 (14.3 %)

Alleles

        

 G

6 (100 %)

64 (86.5 %)

77 (82 %)

41 (89 %)

1.36 (0.61- 3.03), 0.55

33 (78.5 %)

05 (83.3 %)

1.84 (0.70- 4.81),021

 A

10 (13.5 %)

17 (18 %)

05 (11 %)

 

09 (21.5 %)

01 (16.7 %)

 
  1. Hp: Helicobacter pylori; n: number of samples