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Table 1 Percentages of serum proteins of the animals at different times after envenomation

From: Experimental Lachesis muta rhombeata envenomation and effects of soursop (Annona muricata) as natural antivenom

Groups

N a

Albumin (%)b

Alfa-1 (%)b

Alfa-2 (%)b

Beta-1 (%)b

Beta-2 (%)b

Gama (%)b

Control

36

59.84 ± 0.51

15.10 ± 0.72

8.61 ± 0.31

5.76 ± 0.19

8.39 ± 0.18

2.02 ± 0.08

C + AmL

27

59.46 ± 0.67

14.88 ± 0.63

9.67 ± 0.62

5.84 ± 0.19

8.28 ± 0.17

1.92 ± 0.10

C + AmJ

28

59.66 ± 0.66

15.61 ± 0.86

6.60 ± 0.62

6.20 ± 0.23

8.88 ± 0.18

2.32 ± 0.13

LmrV 1h

10

56.14 ± 1.24

18.72 ± 1.17

8.15 ± 0.72

5.69 ± 0.20

8.76 ± 0.31

2.54 ± 0.27

LmrV 6h

10

55.56 ± 0.81*

18.20 ± 0.75

9.47 ± 0.74

6.52 ± 0.43

8.03 ± 0.26

2.21 ± 0.24

LmrV 24h

9

45.60 ± 0.92*

21.22 ± 0.78*

14.82 ± 1.90*

12.33 ± 0.28*

8.80 ± 0.24

1.70 ± 0.27

LmrV + AmL 1h

5

56.50 ± 0.54

20.44 ± 0.45

6.34 ± 0.26

5.76 ± 0.22

9.12 ± 0.22

1.62 ± 0.20

LmrV + AmL 6h

6

54.20 ± 0.41*

19.30 ± 0.52

7.68 ± 0.60

7.25 ± 0.20

9.50 ± 0.36

1.70 ± 0.27

LmrV + AmL 24h

5

40.70 ± 1.81*

17.10 ± 1.36

12.82 ± 0.44*

10.42 ± 0.30*

15.28 ± 2.56*°

2.12 ± 0.24

LmrV + AmJ 1h

6

57.43 ± 0.73

16.55 ± 0.34

9.82 ± 0.58

5.53 ± 0.33

8.50 ± 0.34

2.16 ± 0.14

LmrV + AmJ 6h

6

52.78 ± 1.48*

20.02 ± 0.66

7.28 ± 0.49

6.98 ± 0.68

9.97 ± 0.26

2.66 ± 0.42

LmrV + AmJ 24h

6

40.33 ± 1.81*

19.35 ± 1.01

10.95 ± 0.99

10.87 ± 0.44*

14.70 ± 2.22*°

2.05 ± 0.24

  1. Male Wistar rats were injected with 3 mg of Lachesis muta rhombeata venom, at 1, 6 and 24 h after envenomation (LmrV) and treated respectively with aqueous extract of Annona muricata L. leaves (LmrV + AmL) or Annona muricata L. juice (LmrV + AmJ)
  2. aNumber of animals per group. bPercentages of serum proteins estimated by densitometry, represented by mean ± SEM. * p < 0.05, significant difference compared to control group. ° p < 0.05, significant difference compared to envenomation LmrV group (without treatment)