Table 3 Search of de novo sequenced peptides of sea urchins in PepBank
Peptide | Origin | Function (possible) |
|---|---|---|
DVKL | A. lixula – coelomic fluid | Antibiotic and anticancer |
FLSY | L. variegatus – coelomic fluid | Phospholipase A2 inhibitor |
LDLR | A. lixula – coelomic fluid | Peptide in thrombin-liberated human/eglin (inhibitory activity towards human leukocyte elastase, cathepsin G, porcine pancreatic elastase and alpha-chymotrypsin) |
LGSR | E. lucunter – coelomic fluid | Brain peptide for activation of prothoracic gland, factor VIII activity, toxin Tc61 (scorpion), human neutrophil NADPH oxidase factor 2 |
LLLL | A. lixula – coelomic fluid | Antimicrobial, neuroprotective |
LPPP | E. lucunter – coelomic fluid | Dipeptidyl carboxypeptidase substrate |
LVAL | L. variegatus – spines | Antiviral |
PESL | A. lixula – coelomic fluid | Membrane-bound aminopeptidase P, protein tyrosine kinases |