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Table 1 Scorpion peptides and derivatives with antiviral activity

From: Antiviral activity of animal venom peptides and related compounds

Scorpion Peptide name Virus EC50 Reference
Lychas mucronatus Mucroporin-M1 MeV 7.15 μg/mL (3.52 μM) [39]
  SARS-CoV 14.46 μg/mL (7.12 μM) [39]
  H5N1 2.10 μg/mL (1.03 μM) [39]
  HBV [40]
  HIV-1 [38]
Heterometrus petersii Hp1090 HCV 7.62 μg/mL (5.0 μM) [41]
Hp1036 HSV-1 0.43 ± 0.09 μM [42]
Hp1239 HSV-1 0.41 ± 0.06 μM [42]
Mesobuthus martensii Kn2-7 HIV-1 2.76 μg/mL (1.65 μM) [38]
Bmkn2 HIV-1 [38]
Chaerilus tryznai Ctry2459 HCV 1.84 μg/mL [43]
Ctry2459-H2 HCV 1.08 μg/mL [43]
Ctry2459-H3 HCV 0.85 μg/mL [43]
  1. EC 50 peptide concentration required to reduce virus infection by 50%, HIV-1 human immunodeficiency virus type 1, MeV measles virus, HBV hepatitis B virus, HCV hepatitis C virus, SARS-CoV severe acute respiratory syndrome/coronavirus, H5N1 influenza virus, HSV-1 herpes simplex virus type 1. Adapted from Hmed et al. [8]