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Fig. 1 | Journal of Venomous Animals and Toxins including Tropical Diseases

Fig. 1

From: Multiple uses of fibrin sealant for nervous system treatment following injury and disease

Fig. 1

Schematic view of dorsal and ventral nerve roots. Sensory neurons bring sensory inputs through the dorsal roots, which are transmitted to the motoneurons via interneurons. Motoneurons send their axons through ventral roots that innervate target muscles. Dorsal root lesion and ventral root avulsion have been used to evaluate the efficacy of the CEVAP heterologous fibrin sealant (HFS) for CNS repair and regeneration. The inset shows presynaptic terminals in apposition to motoneurons that retract after injury (synapse pruning). Myelinated axons located in the white matter are highlighted (top left) by using AxonSeg, an open source software for axon morphometry [58]

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