Fig. 1
From: Heterologous fibrin sealant derived from snake venom: from bench to bedside – an overview
a The final common pathway of the human blood-clotting cascade. b The effect of bovine thrombin on human fibrinogen. c The effect of a serine protease (thrombin-like enzyme) extracted from snake venom on animal fibrinogen forming a stable fibrin polymer. Reprinted from “A new fibrin sealant from Crotalus durissus terrificus venom: applications in medicine” by LC Barros et al., J Toxicol Environ Health B Crit Rev, 2009, 12(8), 553–71 [9]. Copyright by Taylor & Francis LLC (http://www.tandfonline.com). Reprinted with permission