Table 1 Alpha-type PLA₂ inhibitors (αPLIs) studied to date

Sequential chromatography on Sephadex G-200, DEAE-cellulose and Blue Sepharose CL-6B

Trimeresurus flavoviridis

TftPLIα

[41]

Sequential chromatography on Sephadex G-200, Mono Q and Blue Sepharose CL-6B

Agkistrodon blomhoffii siniticus

GbPLIα

[42]

Affinity chromatography with Sepharose-immobilized myotoxins (myotoxins I, II, III and IV from B. asper venom)

Bothrops asper

BaMIP

[73]

Affinity chromatography containing myotoxin II isolated from C. godmani venom, coupled to CNBr-activated Sepharose 4B

Cerrophidion godmani

CgMIP-II

[32]

Affinity chromatography containing B. moojeni MjTX-II coupled to CNBr-activated Sepharose 4B

Bothrops moojeni

BmjMIP

[36]

Sequential chromatography on Hi-trap Blue, Mono Q, and Superdex 200

Elaphe quadrivirgata

EqPLIα

[68]

Affinity chromatograph containing myotoxins I and II from A. nummifer coupled to NHS-activated column

Atropoides nummifer

AnMIP

[37]

Affinity chromatography containing B. jararacussu BthTX-I coupled to CNBr-activated Sepharose 4B

Bothrops jararacussu

αBjussuMIP

[38]

Sequential chromatography Blue Sepharose 6FF, Q-Sepharose and Superdex 200 HR10/30

Elaphe climacophora

PLIα

[50]

Affinity chromatography containing BthTX-I, from B. jararacussu, coupled to CNBr-activated Sepharose 4B

Bothrops alternatus

αBaltMIP

[40]