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Table 1 Alpha-type PLA2 inhibitors (αPLIs) studied to date

From: Alpha-type phospholipase A2 inhibitors from snake blood

Purification method Source Name Reference
Sequential chromatography on Sephadex G-200, DEAE-cellulose and Blue Sepharose CL-6B Trimeresurus flavoviridis TftPLIα [41]
Sequential chromatography on Sephadex G-200, Mono Q and Blue Sepharose CL-6B Agkistrodon blomhoffii siniticus GbPLIα [42]
Affinity chromatography with Sepharose-immobilized myotoxins (myotoxins I, II, III and IV from B. asper venom) Bothrops asper BaMIP [73]
Affinity chromatography containing myotoxin II isolated from C. godmani venom, coupled to CNBr-activated Sepharose 4B Cerrophidion godmani CgMIP-II [32]
Affinity chromatography containing B. moojeni MjTX-II coupled to CNBr-activated Sepharose 4B Bothrops moojeni BmjMIP [36]
Sequential chromatography on Hi-trap Blue, Mono Q, and Superdex 200 Elaphe quadrivirgata EqPLIα [68]
Affinity chromatograph containing myotoxins I and II from A. nummifer coupled to NHS-activated column Atropoides nummifer AnMIP [37]
Affinity chromatography containing B. jararacussu BthTX-I coupled to CNBr-activated Sepharose 4B Bothrops jararacussu αBjussuMIP [38]
Sequential chromatography Blue Sepharose 6FF, Q-Sepharose and Superdex 200 HR10/30 Elaphe climacophora PLIα [50]
Affinity chromatography containing BthTX-I, from B. jararacussu, coupled to CNBr-activated Sepharose 4B Bothrops alternatus αBaltMIP [40]