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Table 1 Clinical aspects of newborns from infected mothers with Zika virus during pregnancy

From: Zika virus congenital syndrome: experimental models and clinical aspects

Abnormalities

References

Brain

 

 Ventriculomegaly

[3, 24, 34]

 Cortical and subcortical calcifications

[3, 24, 34, 36, 37, 39, 40, 56]

 Agyria, taquigyria or polymicrogyria

[3, 34, 35]

 Collapsed or dilated ventricle

[3, 56]

 Agenesia

[34]

 Lysencephaly

[24, 34]

 Hypoplasia of cerebellum

[35]

 Hydranencephaly

[55, 56]

 Loss of cerebral parenchyma volume

[34]

 Astroglyosis

[3]

Ocular

 

 Uveitis

[24]

 Retinal degeneration

[24]

 Neuroretinal atrophy

[28]

 Macular atrophy

[60]

 Optic nerve hypoplasia

[58, 60]

 Macular pigment mottling

[28]

 Chorioretinal scar

[28, 58]

Others

 

 Arthrogryposis

[54,55,56]

 Intrauterine growth restriction

[3]

 Congenital contractures

[36]

 Pulmonary hypoplasia

[36]

 Craniofacial malformations

[36]