Quality of horse F(ab’)2 antitoxins and anti-rabies immunoglobulins: protein content and anticomplementary activity

Table 2 Volume and amount of protein of each immunoglobulin incubated with normal human serum (NHS) in vitro

Product	Maximum volume administered to patients [volume (mL)/2.75 L of plasma]	Incubation volume^a [volume (μL)/200 μL of NHS]	Amount of protein (μg)/200 μL of NHS
Anti-botulinum AB	20	1.45	113.5 ± 0.71
Anti-diphteric	120	8.73	1409.0 ± 46.88
Antitetanic	20	1.45	118.8 ± 14.57
Anti-rabies	15	1.09	29.51 ± 1.05

^aThe incubation volume was based on the maximum volume administered to patients, proportionally to the volume of circulating plasma

ISSN: 1678-9199