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Table 2 Volume and amount of protein of each immunoglobulin incubated with normal human serum (NHS) in vitro

From: Quality of horse F(ab’)2 antitoxins and anti-rabies immunoglobulins: protein content and anticomplementary activity

Product Maximum volume administered to patients [volume (mL)/2.75 L of plasma] Incubation volumea [volume (μL)/200 μL of NHS] Amount of protein (μg)/200 μL of NHS
Anti-botulinum AB 20 1.45 113.5 ± 0.71
Anti-diphteric 120 8.73 1409.0 ± 46.88
Antitetanic 20 1.45 118.8 ± 14.57
Anti-rabies 15 1.09 29.51 ± 1.05
  1. aThe incubation volume was based on the maximum volume administered to patients, proportionally to the volume of circulating plasma