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Table 2 Activation and inactivation V1/2 values

From: Mass fingerprinting and electrophysiological analysis of the venom from the scorpion Centruroides hirsutipalpus (Scorpiones: Buthidae)

Sodium channel

V1/2 activation (mV)

V1/2 inactivation (mV)

Control

Venom

Control

Venom

hNav 1.1

−22.4 ± 0.5

−26.5 ± 3.4

−52 ± 0.2

−53 ± 0.2

hNav 1.2

−25 ± 0.3

−43 ± 3

−61.6 ± 0.2

−66.9 ± 0.3

hNav 1.3

−20 ± 0.6

−19.9 ± 0.5

−53.9 ± 0.5

−52.6 ± 0.6

hNav 1.4

−4.2 ± 0.4

−4.4 ± 0.4

− 43.8 ± 0.3

−44.2 ± 1.4

hNav 1.5

−25.7 ± 0.3

−25 ± 0.3

−59.7 ± 0.3

60 ± 0.3

hNav 1.6

−22.8 ± 0.3

− 45.2 ± 1

−56.4 ± 0.3

−62.3 ± 0.2

hNav 1.7

−25.7 ± 0.3

−27 ± 0.4

−71.5 ± 0.4

70.6 ± 0.3

  1. V1/2 = middle activation or inactivation potential