Table 2 Activation and inactivation V1/2 values
Sodium channel | V1/2 activation (mV) | V1/2 inactivation (mV) | ||
|---|---|---|---|---|
Control | Venom | Control | Venom | |
hNav 1.1 | −22.4 ± 0.5 | −26.5 ± 3.4 | −52 ± 0.2 | −53 ± 0.2 |
hNav 1.2 | −25 ± 0.3 | −43 ± 3 | −61.6 ± 0.2 | −66.9 ± 0.3 |
hNav 1.3 | −20 ± 0.6 | −19.9 ± 0.5 | −53.9 ± 0.5 | −52.6 ± 0.6 |
hNav 1.4 | −4.2 ± 0.4 | −4.4 ± 0.4 | − 43.8 ± 0.3 | −44.2 ± 1.4 |
hNav 1.5 | −25.7 ± 0.3 | −25 ± 0.3 | −59.7 ± 0.3 | 60 ± 0.3 |
hNav 1.6 | −22.8 ± 0.3 | − 45.2 ± 1 | −56.4 ± 0.3 | −62.3 ± 0.2 |
hNav 1.7 | −25.7 ± 0.3 | −27 ± 0.4 | −71.5 ± 0.4 | 70.6 ± 0.3 |