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Table 2 Activation and inactivation V1/2 values

From: Mass fingerprinting and electrophysiological analysis of the venom from the scorpion Centruroides hirsutipalpus (Scorpiones: Buthidae)

Sodium channel V1/2 activation (mV) V1/2 inactivation (mV)
Control Venom Control Venom
hNav 1.1 −22.4 ± 0.5 −26.5 ± 3.4 −52 ± 0.2 −53 ± 0.2
hNav 1.2 −25 ± 0.3 −43 ± 3 −61.6 ± 0.2 −66.9 ± 0.3
hNav 1.3 −20 ± 0.6 −19.9 ± 0.5 −53.9 ± 0.5 −52.6 ± 0.6
hNav 1.4 −4.2 ± 0.4 −4.4 ± 0.4 − 43.8 ± 0.3 −44.2 ± 1.4
hNav 1.5 −25.7 ± 0.3 −25 ± 0.3 −59.7 ± 0.3 60 ± 0.3
hNav 1.6 −22.8 ± 0.3 − 45.2 ± 1 −56.4 ± 0.3 −62.3 ± 0.2
hNav 1.7 −25.7 ± 0.3 −27 ± 0.4 −71.5 ± 0.4 70.6 ± 0.3
  1. V1/2 = middle activation or inactivation potential
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Journal of Venomous Animals and Toxins including Tropical Diseases

ISSN: 1678-9199

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