Fig. 1
From: Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study
Evaluation of the bioenergetic parameters of T. cruzi. a Mitochondrial membrane potential of T. cruzi trypomastigotes treated with sertraline for 1 h at 2 μM, positive control (FCCP) and negative control (untreated cells). The fluorescence was determined using a fluorimetric microplate reader (FilterMax F5 Multi-Mode Microplate Reader) at 540 and 595 nm for excitation and emission, respectively. *** (p < 0.05); b Evaluation of the ATP levels of T. cruzi incubated for 1 h with sertraline at 2 μM. The levels were measured in a spectroluminometer plate reader (FilterMax F5 Multi-Mode Microplate Reader) using the ATP determination Kit (Life technologies). *** p < 0.05