From: Activity of the antiarrhythmic drug amiodarone against Leishmania (L.) infantum: an in vitro and in vivo approach
Drugs
Promastigotes
IC50 (μM) (95%CI)
Amastigotes
Cytotoxicity
CC50 (μM) (95%CI)
SI
Amiodarone
10.5
(9.5–11.7)
0.5
(0.1–2.0)
30.9
(12.5–76.1)
56.2
Miltefosine
16.8 (15.4–17.5)
17.8 (11.6–24.6)
122.0 (94.8–157.0)
6.8