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Fig. 10 | Journal of Venomous Animals and Toxins including Tropical Diseases

Fig. 10

From: Intravitreal injection of the synthetic peptide LyeTx I b, derived from a spider toxin, into the rabbit eye is safe and prevents neovascularization in a chorio-allantoic membrane model

Fig. 10

LyeTx I b prevents neovascularization on the CAM: Sequence of photographs illustrating the effect of (a) Vehicle, (b) Bevacizumab 0.5 mg/mL, (c) LyeTx I b 0.54 μM, (d) LyeTx I b 0.72 μM, (e) LyeTx I b 2.17 μM and (f) LyeTx I b 2.89 μM on the CAM over a 72-h period. g Graph shows the measure of vascularization after exposure to untreated eggs (Vehicle) or treatment with LyeTx I b (0.54 μM, 0.72 μM, b 2.17 μM or 2.89 μM). Data represent the ± SEM of number of pixels of twelve independent experiments. * indicates significant difference as compared to vehicle (p < 0.05). # indicates significant difference as compared to Bevacizumab (p < 0.05). n.s. indicates no significant difference as compared to vehicle (p > 0.05). Abbreviations: SEM, standard error of the mean

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