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Fig. 11 | Journal of Venomous Animals and Toxins including Tropical Diseases

Fig. 11

From: Intravitreal injection of the synthetic peptide LyeTx I b, derived from a spider toxin, into the rabbit eye is safe and prevents neovascularization in a chorio-allantoic membrane model

Fig. 11

LyeTx I b prevents neovascularization keeping the morphology integrity of CAM: A: Histological images illustrating CAM mesoderm after exposure to (a) Vehicle, (b) Bevacizumab 0.5 mg/mL, (c) LyeTx I b 0.54 μM, (d) LyeTx I b 0.72 μM, (e) LyeTx I b 2.17 μM and (f) LyeTx I b 2.89 μM over a 72-h period. (a and c) Vasculogenic reaction: simultaneous and co-localized vasculogenesis and hematopoiesis is observed. b, d, e and f show reduction in vasculogenesis and hematopoiesis

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Journal of Venomous Animals and Toxins including Tropical Diseases

ISSN: 1678-9199

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