Fig. 10
From: Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom
Evaluation of the cytotoxic effects induced by BJ-PLA2-I on normal and tumor cells. Cell viability of PBMC (a), HL-60 (b) and HepG2 (c) was assessed by the MTT method after a 24 h stimulation period with BJ-PLA2-I at different concentrations (2.5–160 μg/mL). Cells treated only with sterile PBS were used as negative controls (NC). The positive controls (PC) received cisplatin (Incel, Darrow®) at the final concentration of 250 μg/mL. Results were expressed as mean percentages (in relation to the negative control, considered as 100%) ± SD (n = 3) of two independent experiments. *p < 0.05 compared to the negative control (NC)