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Table 5 Analysis of Δѱm. index of variation (IV) of L. infantum promastigotes treated with LQBs

From: Second-generation pterocarpanquinones: synthesis and antileishmanial activity

Compounds μM Index of variation a
Control 0 0
LQB 187 (2A) 1.25 −0.103 ± 0.16
2.5 −0.368 ± 0.03
LQB 182 (2B) 1.25 −0.397 ± 0.07
2.5 −0.402 ± 0.04
LQB 236 (2C) 1.25 −0.360 ± 0.16
2.5 −0.258 ± 0.17
LQB 168 (2D) 1.25 −0.369 ± 0.08
2.5 −0.194 ± 0.18
LQB 474 (2E) 1.25 −0.582 ± 0.1
2.5 −0.701 ± 0.01
LQB 475 (2F) 1.25 −0.668 ± 0.01
2.5 −0.707 ± 0.01
FCCP 20 −0.727 ± 0.01
  1. Values refer to the mean and standard deviation of three experiments
  2. MT median fluorescence of treated parasites, MC median fluorescence of control parasites
  3. a The changes in the fluorescence intensity of rhodamine 123 were quantified from the index of variation obtained by the equation (MT – MC) / MC
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Journal of Venomous Animals and Toxins including Tropical Diseases

ISSN: 1678-9199

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