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  1. Research

    In vitro characterization of jellyfish venom fibrin(ogen)olytic enzymes from Nemopilema nomurai

    Because jellyfish are capable of provoking envenomation in humans, they are considered hazardous organisms. Although the effects of their toxins are a matter of concern, information on the venom components, bi...

    Seong Kyeong Bae, Hyunkyoung Lee, Yunwi Heo, Min Jung Pyo, Indu Choudhary, Chang Hoon Han, Won Duk Yoon, Changkeun Kang and Euikyung Kim

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:35

    Published on: 19 July 2017

  2. Research

    Mathematical modelling of vector-borne diseases and insecticide resistance evolution

    Vector-borne diseases are important public health issues and, consequently, in silico models that simulate them can be useful. The susceptible-infected-recovered (SIR) model simulates the population dynamics o...

    Maria Laura Gabriel Kuniyoshi and Fernando Luiz Pio dos Santos

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:34

    Published on: 6 July 2017

  3. Research

    Isolation and biochemical characterization of bradykinin-potentiating peptides from Bitis gabonica rhinoceros

    Venoms represent a still underexplored reservoir of bioactive components that might mitigate or cure diseases in conditions in which conventional therapy is ineffective. The bradykinin-potentiating peptides (B...

    Tamara M. Fucase, Juliana M. Sciani, Ingrid Cavalcante, Vincent L. Viala, Bruno B. Chagas, Daniel C. Pimenta and Patrick J. Spencer

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:33

    Published on: 26 June 2017

  4. Review

    Jaburetox: update on a urease-derived peptide

    Urease from Canavalia ensiformis seeds was the first enzyme ever to be crystallized, in 1926. These proteins, found in plants, bacteria and fungi, present different biological properties including catalytic hydro...

    Arlete Beatriz Becker-Ritt, Camila Saretta Portugal and Célia Regina Carlini

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:32

    Published on: 15 June 2017

  5. Review

    Perinatal effects of scorpion venoms: maternal and offspring development

    Scorpion envenomation is a public health problem, especially in tropical and subtropical countries. Considering the high incidence of scorpionism in some areas, pregnant women and nursing mothers may be possib...

    Ana Leticia Coronado Dorce, Adriana do Nascimento Martins, Valquiria Abrão Coronado Dorce and Ana Leonor Abrahão Nencioni

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:31

    Published on: 14 June 2017

  6. Research

    Ergosterol isolated from the basidiomycete Pleurotus salmoneostramineus affects Trypanosoma cruzi plasma membrane and mitochondria

    Major drawbacks of the available treatment against Chagas disease (American trypanosomiasis) include its toxicity and therapeutic inefficiency in the chronic phase of the infection, which makes it a concern am...

    Tatiana Rodrigues Alexandre, Marta Lopes Lima, Mariana Kolos Galuppo, Juliana Tonini Mesquita, Matilia Ana do Nascimento, Augusto Leonardo dos Santos, Patricia Sartorelli, Daniel Carvalho Pimenta and Andre Gustavo Tempone

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:30

    Published on: 30 May 2017

  7. Research

    Isolation of biologically active peptides from the venom of Japanese carpenter bee, Xylocopa appendiculata

    Mass spectrometry-guided venom peptide profiling is a powerful tool to explore novel substances from venomous animals in a highly sensitive manner. In this study, this peptide profiling approach is successfull...

    Hiroko Kawakami, Shin G. Goto, Kazuya Murata, Hideaki Matsuda, Yasushi Shigeri, Tomohiro Imura, Hidetoshi Inagaki and Tetsuro Shinada

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:29

    Published on: 23 May 2017

  8. Short report

    Antivenomics as a tool to improve the neutralizing capacity of the crotalic antivenom: a study with crotamine

    Snakebite treatment requires administration of an appropriate antivenom that should contain antibodies capable of neutralizing the venom. To achieve this goal, antivenom production must start from a suitable i...

    Ricardo Teixeira-Araújo, Patrícia Castanheira, Leonora Brazil-Más, Francisco Pontes, Moema Leitão de Araújo, Maria Lucia Machado Alves, Russolina Benedeta Zingali and Carlos Correa-Netto

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:28

    Published on: 12 May 2017

  9. Review

    Strategies in ‘snake venomics’ aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

    This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and discusses how these may be combined through diverse experimental approaches with the goal of achie...

    Bruno Lomonte and Juan J. Calvete

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:26

    Published on: 28 April 2017

  10. Review

    Protein-species quantitative venomics: looking through a crystal ball

    In this paper we discuss recent significant developments in the field of venom research, specifically the emergence of top-down proteomic applications that allow achieving compositional resolution at the level...

    Juan J. Calvete, Daniel Petras, Francisco Calderón-Celis, Bruno Lomonte, Jorge Ruiz Encinar and Alfredo Sanz-Medel

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:27

    Published on: 28 April 2017

  11. Case report

    Neurological complications and death in children with dengue virus infection: report of two cases

    Dengue virus infection can have different complications; the best known is hemorrhagic dengue fever. However, other effects such as neurological disorders may endanger the lives of patients. Dengue neurologica...

    Neydi Osnaya-Romero, Maria-Gabriela Perez-Guille, Sandra Andrade-García, Erika Gonzalez-Vargas, Rebeca Borgaro-Payro, Sandra Villagomez-Martinez, José de Jesús Ortega-Maldonado and Jose Luis Arredondo-García

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:25

    Published on: 27 April 2017

  12. Research Article

    Rattlesnake Crotalus molossus nigrescens venom induces oxidative stress on human erythrocytes

    Globally, snake envenomation is a well-known cause of death and morbidity. In many cases of snakebite, myonecrosis, dermonecrosis, hemorrhage and neurotoxicity are present. Some of these symptoms may be provok...

    David Meléndez-Martínez, Juan Manuel Muñoz, Guillermo Barraza-Garza, Martha Sandra Cruz-Peréz, Ana Gatica-Colima, Emilio Alvarez-Parrilla and Luis Fernando Plenge-Tellechea

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:24

    Published on: 21 April 2017

  13. Short report

    Interleukin 8 (-251 T>A) polymorphism in children and teenagers infected with Helicobacter pylori

    Helicobacter pylori (H. pylori) is a gram-negative bacterium that colonizes the human stomach and causes a variety of gastric diseases. This study evaluated the correlations between th...

    Marina Saes, Roger Willian de Labio, Lucas Trevizani Rasmussen and Spencer Luiz Marques Payão

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:23

    Published on: 8 April 2017

  14. Research

    Preparation and neutralization efficacy of IgY antibodies raised against Deinagkistrodon acutus venom

    The five-paced pit viper (Deinagkistrodon acutus), endemic to China and northern Vietnam, is responsible for most snakebites in the Chinese territory. Antivenom produced from horses is the main treatment for snak...

    Jinhua Liu, Qiyi He, Wenwen Wang, Bin Zhou, Bo Li, Yingfeng Zhang, Cong Luo, Diancheng Chen, Jia Tang and Xiaodong Yu

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:22

    Published on: 4 April 2017

  15. Review

    Heterologous fibrin sealant derived from snake venom: from bench to bedside – an overview

    Hemostatic and adhesive agents date back to World War II, when homologous fibrin sealant came onto scene. Considering that infectious diseases can be transmitted via human blood, a new heterologous fibrin seal...

    Rui Seabra Ferreira Jr, Luciana Curtolo de Barros, Luciana Patrícia Fernandes Abbade, Silvia Regina Catharino Sartori Barraviera, Maria Regina Cavariani Silvares, Leticia Gomes de Pontes, Lucilene Delazari dos Santos and Benedito Barraviera

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:21

    Published on: 4 April 2017

  16. Case report

    Deinagkistrodon acutus envenomation: a report of three cases

    Deinagkistrodon acutus envenomation is associated with severe hematological and wound complications but is rarely described.

    Chin-Lung Cheng, Yan-Chiao Mao, Po-Yu Liu, Liao-Chun Chiang, Shu-Chen Liao and Chen-Chang Yang

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:20

    Published on: 23 March 2017

  17. Research

    Agaricus brasiliensis polysaccharides stimulate human monocytes to capture Candida albicans, express toll-like receptors 2 and 4, and produce pro-inflammatory cytokines

    Agaricus brasiliensis is a medicinal mushroom with immunomodulatory and antitumor activities attributed to the β-glucans presented in the polysaccharide fraction of its fruiting body. ...

    Priscila Raquel Martins, Ângela Maria Victoriano de Campos Soares, Andrea Vanessa da Silva Pinto Domeneghini, Márjorie Assis Golim and Ramon Kaneno

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:17

    Published on: 23 March 2017

  18. Review

    Alpha-type phospholipase A2 inhibitors from snake blood

    It is of popular and scientific knowledge that toxins from snake venom (among them the PLA2 and myotoxins) are neutralized by various compounds, such as antibodies and proteins purified from animal blood. Venomou...

    Norival A. Santos-Filho and Claudia T. Santos

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:19

    Published on: 23 March 2017

  19. Research

    Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect

    Arthritis is a set of inflammatory conditions that induce aching, stiffness, swelling, pain and may cause functional disability with severe consequences to the patient’s lives. These are multi-mediated patholo...

    Renata Gonçalves Dias, Sandra Coccuzzo Sampaio, Morena Brazil Sant’Anna, Fernando Queiroz Cunha, José María Gutiérrez, Bruno Lomonte, Yara Cury and Gisele Picolo

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:18

    Published on: 23 March 2017

  20. Case report

    Reversible atrial fibrillation following Crotalinae envenomation

    Cardiotoxicity is a documented complication of Crotalinae envenomation. Reported cardiac complications following snake envenomation have included acute myocardial infarction, electrocardiogram abnormalities an...

    Dan Quan and Kenneth Zurcher

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:16

    Published on: 21 March 2017

  21. Research

    A clinical trial protocol to treat massive Africanized honeybee (Apis mellifera) attack with a new apilic antivenom

    Envenomation caused by multiple stings from Africanized honeybees Apis mellifera constitutes a public health problem in the Americas. In 2015, the Brazilian Ministry of Health reported 13,597 accidents (incidence...

    Alexandre Naime Barbosa, Leslie Boyer, Jean-Philippe Chippaux, Natalia Bronzatto Medolago, Carlos Antonio Caramori, Ariane Gomes Paixão, João Paulo Vasconcelos Poli, Mônica Bannwart Mendes, Lucilene Delazari dos Santos, Rui Seabra Ferreira Jr and Benedito Barraviera

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:14

    Published on: 16 March 2017

  22. Review

    Multiple uses of fibrin sealant for nervous system treatment following injury and disease

    Lesions to the nervous system often produce hemorrhage and tissue loss that are difficult, if not impossible, to repair. Therefore, scar formation, inflammation and cavitation take place, expanding the lesion ...

    Natalia Perussi Biscola, Luciana Politti Cartarozzi, Suzana Ulian-Benitez, Roberta Barbizan, Mateus Vidigal Castro, Aline Barroso Spejo, Rui Seabra Ferreira Jr., Benedito Barraviera and Alexandre Leite Rodrigues Oliveira

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:13

    Published on: 14 March 2017

  23. Research

    Can anti-bothropstoxin-I antibodies discriminate between Bothrops jararaca and Bothrops jararacussu venoms?

    Snakes of the genus Bothrops, popularly known as pit vipers, are responsible for most cases of snakebite in Brazil. Within this genus, Bothrops jararacussu and B. jararaca deserve special attention due to the sev...

    Ricardo Teixeira Araujo, Carlos Corrêa-Netto, Leonora Brazil-Más, Caio Raony Farina Silveira, Irene Fernandes and Russolina Benedeta Zingali

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:12

    Published on: 11 March 2017

  24. Research

    Standardization and validation of Dot-ELISA assay for Paracoccidioides brasiliensis antibody detection

    Paracoccidioidomycosis (PCM) is a neglected systemic mycosis caused by a dimorphic fungus of the Paracoccidioides genus. The standard diagnosis is based on isolation of the fungi in culture, and by microscopic vi...

    Camila Mika Kamikawa, Rinaldo Poncio Mendes and Adriana Pardini Vicentini

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:11

    Published on: 15 February 2017

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