Figure 4

Effects of different doses of MVIIC on biochemical parameters. Mean number ± SD of alanine aminotransferase (ALT) (U/L), aspartate aminotransferase (AST) (U/L), urea (mg/dL) and creatinine (mg/dL) in different times (preoperatively and eight days after injection) (p < 0.05). Controls were injected with sterile water (PLA) and other groups received different doses of MVIIC (15, 30, 60 and 120 pmol). ALT, AST, urea and creatinine normal values are, respectively, 19–48 U/L, 63–175 U/L, 10.7-20 mg/dL and 0.3-0.5 mg/dL, as described by Giknis and Clifford [39].