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  1. Review

    Strategies in ‘snake venomics’ aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

    This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and discusses how these may be combined through diverse experimental approaches with the goal of achie...

    Bruno Lomonte and Juan J. Calvete

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:26

    Published on: 28 April 2017

  2. Review

    Protein-species quantitative venomics: looking through a crystal ball

    In this paper we discuss recent significant developments in the field of venom research, specifically the emergence of top-down proteomic applications that allow achieving compositional resolution at the level...

    Juan J. Calvete, Daniel Petras, Francisco Calderón-Celis, Bruno Lomonte, Jorge Ruiz Encinar and Alfredo Sanz-Medel

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:27

    Published on: 28 April 2017

  3. Case report

    Neurological complications and death in children with dengue virus infection: report of two cases

    Dengue virus infection can have different complications; the best known is hemorrhagic dengue fever. However, other effects such as neurological disorders may endanger the lives of patients. Dengue neurologica...

    Neydi Osnaya-Romero, Maria-Gabriela Perez-Guille, Sandra Andrade-García, Erika Gonzalez-Vargas, Rebeca Borgaro-Payro, Sandra Villagomez-Martinez, José de Jesús Ortega-Maldonado and Jose Luis Arredondo-García

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:25

    Published on: 27 April 2017

  4. Research Article

    Rattlesnake Crotalus molossus nigrescens venom induces oxidative stress on human erythrocytes

    Globally, snake envenomation is a well-known cause of death and morbidity. In many cases of snakebite, myonecrosis, dermonecrosis, hemorrhage and neurotoxicity are present. Some of these symptoms may be provok...

    David Meléndez-Martínez, Juan Manuel Muñoz, Guillermo Barraza-Garza, Martha Sandra Cruz-Peréz, Ana Gatica-Colima, Emilio Alvarez-Parrilla and Luis Fernando Plenge-Tellechea

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:24

    Published on: 21 April 2017

  5. Short report

    Interleukin 8 (-251 T>A) polymorphism in children and teenagers infected with Helicobacter pylori

    Helicobacter pylori (H. pylori) is a gram-negative bacterium that colonizes the human stomach and causes a variety of gastric diseases. This study evaluated the correlations between th...

    Marina Saes, Roger Willian de Labio, Lucas Trevizani Rasmussen and Spencer Luiz Marques Payão

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:23

    Published on: 8 April 2017

  6. Research

    Preparation and neutralization efficacy of IgY antibodies raised against Deinagkistrodon acutus venom

    The five-paced pit viper (Deinagkistrodon acutus), endemic to China and northern Vietnam, is responsible for most snakebites in the Chinese territory. Antivenom produced from horses is the main treatment for snak...

    Jinhua Liu, Qiyi He, Wenwen Wang, Bin Zhou, Bo Li, Yingfeng Zhang, Cong Luo, Diancheng Chen, Jia Tang and Xiaodong Yu

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:22

    Published on: 4 April 2017

  7. Review

    Heterologous fibrin sealant derived from snake venom: from bench to bedside – an overview

    Hemostatic and adhesive agents date back to World War II, when homologous fibrin sealant came onto scene. Considering that infectious diseases can be transmitted via human blood, a new heterologous fibrin seal...

    Rui Seabra Ferreira, Luciana Curtolo de Barros, Luciana Patrícia Fernandes Abbade, Silvia Regina Catharino Sartori Barraviera, Maria Regina Cavariani Silvares, Leticia Gomes de Pontes, Lucilene Delazari dos Santos and Benedito Barraviera

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:21

    Published on: 4 April 2017

  8. Case report

    Deinagkistrodon acutus envenomation: a report of three cases

    Deinagkistrodon acutus envenomation is associated with severe hematological and wound complications but is rarely described.

    Chin-Lung Cheng, Yan-Chiao Mao, Po-Yu Liu, Liao-Chun Chiang, Shu-Chen Liao and Chen-Chang Yang

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:20

    Published on: 23 March 2017

  9. Research

    Agaricus brasiliensis polysaccharides stimulate human monocytes to capture Candida albicans, express toll-like receptors 2 and 4, and produce pro-inflammatory cytokines

    Agaricus brasiliensis is a medicinal mushroom with immunomodulatory and antitumor activities attributed to the β-glucans presented in the polysaccharide fraction of its fruiting body. ...

    Priscila Raquel Martins, Ângela Maria Victoriano de Campos Soares, Andrea Vanessa da Silva Pinto Domeneghini, Márjorie Assis Golim and Ramon Kaneno

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:17

    Published on: 23 March 2017

  10. Review

    Alpha-type phospholipase A2 inhibitors from snake blood

    It is of popular and scientific knowledge that toxins from snake venom (among them the PLA2 and myotoxins) are neutralized by various compounds, such as antibodies and proteins purified from animal blood. Venomou...

    Norival A. Santos-Filho and Claudia T. Santos

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:19

    Published on: 23 March 2017

  11. Research

    Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect

    Arthritis is a set of inflammatory conditions that induce aching, stiffness, swelling, pain and may cause functional disability with severe consequences to the patient’s lives. These are multi-mediated patholo...

    Renata Gonçalves Dias, Sandra Coccuzzo Sampaio, Morena Brazil Sant’Anna, Fernando Queiroz Cunha, José María Gutiérrez, Bruno Lomonte, Yara Cury and Gisele Picolo

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:18

    Published on: 23 March 2017

  12. Case report

    Reversible atrial fibrillation following Crotalinae envenomation

    Cardiotoxicity is a documented complication of Crotalinae envenomation. Reported cardiac complications following snake envenomation have included acute myocardial infarction, electrocardiogram abnormalities an...

    Dan Quan and Kenneth Zurcher

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:16

    Published on: 21 March 2017

  13. Research

    A clinical trial protocol to treat massive Africanized honeybee (Apis mellifera) attack with a new apilic antivenom

    Envenomation caused by multiple stings from Africanized honeybees Apis mellifera constitutes a public health problem in the Americas. In 2015, the Brazilian Ministry of Health reported 13,597 accidents (incidence...

    Alexandre Naime Barbosa, Leslie Boyer, Jean-Philippe Chippaux, Natalia Bronzatto Medolago, Carlos Antonio Caramori, Ariane Gomes Paixão, João Paulo Vasconcelos Poli, Mônica Bannwart Mendes, Lucilene Delazari dos Santos, Rui Seabra Ferreira and Benedito Barraviera

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:14

    Published on: 16 March 2017

  14. Review

    Multiple uses of fibrin sealant for nervous system treatment following injury and disease

    Lesions to the nervous system often produce hemorrhage and tissue loss that are difficult, if not impossible, to repair. Therefore, scar formation, inflammation and cavitation take place, expanding the lesion ...

    Natalia Perussi Biscola, Luciana Politti Cartarozzi, Suzana Ulian-Benitez, Roberta Barbizan, Mateus Vidigal Castro, Aline Barroso Spejo, Rui Seabra Ferreira, Benedito Barraviera and Alexandre Leite Rodrigues Oliveira

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:13

    Published on: 14 March 2017

  15. Research

    Can anti-bothropstoxin-I antibodies discriminate between Bothrops jararaca and Bothrops jararacussu venoms?

    Snakes of the genus Bothrops, popularly known as pit vipers, are responsible for most cases of snakebite in Brazil. Within this genus, Bothrops jararacussu and B. jararaca deserve special attention due to the sev...

    Ricardo Teixeira Araujo, Carlos Corrêa-Netto, Leonora Brazil-Más, Caio Raony Farina Silveira, Irene Fernandes and Russolina Benedeta Zingali

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:12

    Published on: 11 March 2017

  16. Research

    Standardization and validation of Dot-ELISA assay for Paracoccidioides brasiliensis antibody detection

    Paracoccidioidomycosis (PCM) is a neglected systemic mycosis caused by a dimorphic fungus of the Paracoccidioides genus. The standard diagnosis is based on isolation of the fungi in culture, and by microscopic vi...

    Camila Mika Kamikawa, Rinaldo Poncio Mendes and Adriana Pardini Vicentini

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:11

    Published on: 15 February 2017

  17. Case report

    Envenomation by the red-tailed coral snake (Micrurus mipartitus) in Colombia

    Although the red-tailed coral snake (Micrurus mipartitus) is widely distributed in Colombia and its venom is highly neurotoxic and life threatening, envenomation by this species is rare. Therefore, this report ma...

    Carlos A. Cañas, Fernando Castro-Herrera and Santiago Castaño-Valencia

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:9

    Published on: 14 February 2017

  18. Research

    Hematological and plasma biochemical parameters in a wild population of Naja naja (Linnaeus, 1758) in Sri Lanka

    Hematological studies of any animal species comprise an important diagnostic method in veterinary medicine and an essential tool for the conservation of species. In Sri Lanka, this essential technique has been...

    Duminda S. B. Dissanayake, Lasanthika D. Thewarage, Rathnayake M. P. Manel Rathnayake, Senanayake A. M. Kularatne, Jamburagoda G. Shirani Ranasinghe and Rajapakse P. V. Jayantha Rajapakse

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:8

    Published on: 13 February 2017

  19. Research

    Structural determinants of the hyperalgesic activity of myotoxic Lys49-phospholipase A2

    Bothropstoxin-I (BthTx-I) is a Lys49-phospholipase A2 (Lys49-PLA2) from the venom of Bothrops jararacussu, which despite of the lack of catalytic activity induces myotoxicity, inflammation and pain. The C-termina...

    Vanessa Olzon Zambelli, Lucimara Chioato, Vanessa Pacciari Gutierrez, Richard John Ward and Yara Cury

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:7

    Published on: 10 February 2017

  20. Review

    Highlights in the knowledge of brown spider toxins

    Brown spiders are venomous arthropods that use their venom for predation and defense. In humans, bites of these animals provoke injuries including dermonecrosis with gravitational spread of lesions, hematologi...

    Daniele Chaves-Moreira, Andrea Senff-Ribeiro, Ana Carolina Martins Wille, Luiza Helena Gremski, Olga Meiri Chaim and Silvio Sanches Veiga

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:6

    Published on: 8 February 2017

  21. Research

    Ocellatin peptides from the skin secretion of the South American frog Leptodactylus labyrinthicus (Leptodactylidae): characterization, antimicrobial activities and membrane interactions

    The availability of antimicrobial peptides from several different natural sources has opened an avenue for the discovery of new biologically active molecules. To the best of our knowledge, only two peptides is...

    Karla A. G. Gusmão, Daniel M. dos Santos, Virgílio M. Santos, María Esperanza Cortés, Pablo V. M. Reis, Vera L. Santos, Dorila Piló-Veloso, Rodrigo M. Verly, Maria Elena de Lima and Jarbas M. Resende

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:4

    Published on: 19 January 2017

  22. Review

    Antiviral activity of animal venom peptides and related compounds

    Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense. Although a large number of compounds have...

    Élida Cleyse Gomes da Mata, Caroline Barbosa Farias Mourão, Marisa Rangel and Elisabeth Ferroni Schwartz

    Journal of Venomous Animals and Toxins including Tropical Diseases 2017 23:3

    Published on: 6 January 2017

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