Table 2 Frequency of genes cagA and dupA and genotypes of vacA in H. pylori strains isolated from 105 adults and 100 children with gastric chronic and normal gastric mucosa
From: Association among H. pylori virulence markers dupA, cagA and vacA in Brazilian patients
Genes | N (%) | Samples from N (%) | Histopathology | ||||
|---|---|---|---|---|---|---|---|
Chronic gastritis | NGT | ||||||
Total | Adults | Children | Adults | Children | Adults | Children | |
cagA + | 98 (47.8) | 51 (48.6) | 47 (47) | 47 (30.7) | 26 (16.9) | 1 (7.7) | 4 (30.75) |
cagA – | 107 (52.2) | 54 (51.4) | 53 (53) | 48 (31.4) | 32 (21) | 1 (7.7) | 7 (53.85) |
dupA + | 85 (41.4) | 48 (45.7) | 37 (37) | 44 (28.7) | 26 (16.9) | 1 (7.7) | 2 (15.4) |
dupA – | 120 (58.6) | 57 (54.3) | 63 (63) | 51 (33.3) | 32 (21) | 1 (7.7) | 9 (69.2) |
s1/m1 | 103 (50.2) | 58 (55.2) | 45 (45) | 54 (35.3) | 26 (16.9) | 2 (15.4) | 4 (30.75) |
s2/m2 | 75 (36.6) | 33 (31.4) | 42 (42) | 28 (18.4) | 26 (16.9) | 0 (–) | 4 (30.75) |
s1/m2 | 17 (8.3) | 10 (9.5) | 7 (7) | 10 (6.5) | 4 (2.7) | 0 (–) | 2 (15.4) |
s2/m1 | 1 (0.5) | 0 (–) | 1 (1) | 0 (–) | 0 (–) | 0 (–) | 0 (–) |
s1/s2/m1/m2 | 9 (4.4) | 4 (3.9) | 5 (5) | 3 (1.9) | 2 (1.4) | 0 (–) | 1 (7.7) |
Total | 205 (100) | 105 (100) | 100 (100) | 153 (100) | 13 (100) | ||