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Table 1 Yields and major conditions for reactions shown in Scheme 1

From: Second-generation pterocarpanquinones: synthesis and antileishmanial activity

Entry Heat Cond. a 2 (%)
1 A 2a (20%)
2 MW b A 2a (31%)
3 B 2a (57%)
4 MW b B 2a (50%)
5 C 2a (65%)
6 D 2e (47%)
7 D 2e (46%)
  1. a Conditions: A – Pd(OAc)2 (10 mol%), Ag2CO3 (1.5 equiv.), acetone, reflux, 18 h; B - Pd(OAc)2 (10 mol%), Ag2CO3 (1.5 equiv.), pinacolone, reflux, 18 h; C - Pd(OAc)2 (10 mol%), Ag2CO3 (1.1 equiv.), PEG-400, 140 °C, 10 min.; D - Pd(OAc)2 (10 mol%), Ag2CO3 (1.1 equiv.), PEG-400, 90 °C, 10 min
  2. b MW: 40 W, 60 °C (acetone) or 110 °C (pinacolone), 40 min