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  • Letter to the Editor
  • Open Access

Envenomation by caterpillars (erucism): proposal for simple pain relief treatment

Journal of Venomous Animals and Toxins including Tropical Diseases201420:21

  • Received: 16 April 2014
  • Accepted: 22 April 2014
  • Published:


  • Lidocaine
  • Tramadol
  • Dipyrone
  • Prilocaine
  • Oral Analgesic

To the editor

Erucism is the name given to injuries caused by moth larvae in humans. The lesions are provoked by caterpillar bristles filled with toxins that penetrate the skin [14]. The bristles are hollow and when they enter the skin and break, toxins that contain thermolabile proteins, proteolytic enzymes and histamine are released [2]. The shape of bristles indicates the families of caterpillars mainly associated with injuries: Megalopygidae (fine setae throughout the body) and Saturniidae (setae in small pine tree format, see Figure 1) [3]. The toxins cause immediate severe pain, erythema, edema and immediate lymphangitis (Figure 1). In later stages, there may be vesicles, bullae, erosions, petechiae, superficial skin necrosis, and ulcerations [4]. Some genera (Lonomia, Periga) can cause severe hemorrhagic syndromes, but most manifestations are limited to excruciating pain and mild to moderate local inflammation [14].
Figure 1
Figure 1

Caterpillar of the Megalopygidae family (A), Saturniidae family (B) and caterpillar envenomations (C, D) showing mild local inflammation that caused intense pain. Photos: Vidal Haddad Junior.

Treatment for such injuries is based on cold water compresses and oral analgesics (dipyrone is the rule, but the use of potent analgesics, such as tramadol hydrochloride may be required). When painkillers do not control the pain, nerve anesthetic blockade (lidocaine 4.0 mL for adults) may be employed [14]. Based on our past experience, we suggest using serial application of topical commercial anesthetics with 0.25% lidocaine and 0.25% prilocaine in order to greatly decrease or eliminate the pain, these drugs take effect in about half an hour and last for several hours [1, 4]. They are easy to apply, does not interfere with the approach adopted for this kind of accident, and it is especially useful for children and patients whose lesion sites do not allow blockades.


Authors’ Affiliations

Departamento de Dermatologia e Radiologia, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista (UNESP), Caixa Postal 557, Botucatu, SP, 18.618-000, Brasil


  1. Haddad V Jr, Cardoso JLC: Erucismo e lepidopterismo. In Animais peçonhentos no Brasil: biologia, clínica e terapêutica dos acidentes. Edited by: Cardoso JLC, Franca FOS, Wen FH, Malaque CMS, Haddad VJr. São Paulo: Sarvier; 2003:236–239.Google Scholar
  2. Goldman L, Sawyer F, Levine A, Goldman J, Goldman S, Spinanger J: Investigative studies of skin irritations from caterpillars. J Invest Dermatol 1960, 34: 67–79.PubMedGoogle Scholar
  3. Cardoso AEC, Haddad V Jr: Acidentes por lepidópteros (larvas e adultos de mariposas): estudo dos aspectos epidemiológicos, clínicos e terapêuticos. An Bras Dermatol 2005, 80(6):571–578. 10.1590/S0365-05962005000700002View ArticleGoogle Scholar
  4. Haddad V Jr, Cardoso JL, Lupi O, Tyring SK: Tropical dermatology: venomous arthropods and human skin: part I: insecta. J Am Acad Dermatol 2012, 67(3):331. e1–14View ArticlePubMedGoogle Scholar


© Haddad and Lastória; licensee BioMed Central Ltd. 2014

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