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Table 3 Pharmmapper results

From: 4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents

Target PDB Code Ligand Compounds Max z’score valuea Function
S-Methyl-5-thioadenosine phosphorylase 1CG6 All derivatives 3.69 Nucleotide transport and metabolism
Adenosine deaminase 1 V79/1 V89 All but compound 3 4.72 Nucleotide transport and metabolism
UvrABC System Protein B 1C40 All but compound 4 3.59 Replication, recombination, and repair
Dihydrofolate reductase 1IA2 All but compound 4 3.12 Coenzyme transport and metabolism
Queuine t-RNA-ribosyltransferase 1Q66 All but compounds 3 and 4 3.02 Translation, ribosomal structure and biogenesis
  1. (a) among all compounds tested